Symbol
Name
ID

Fgfr2
fibroblast growth factor receptor 2
MGI:95523

Phenotype annotations related to endocrine/exocrine glands

*	Aspects of the system are reported to show a normal phenotype.
	Darker colors indicate more annotations

Human Phenotypes	Ectopic posterior pituitary
Disease(s) Associated with FGFR2	Ectopic posterior pituitary
craniosynostosis

Mouse Phenotypes

abnormal nasal gland morphology

abnormal lateral nasal gland morphology

abnormal salivary gland morphology

abnormal submandibular duct morphology

absent submandibular gland

submandibular gland hypoplasia

endocrine/exocrine gland phenotype

abnormal adrenal gland development

abnormal Rathke's pouch apoptosis

abnormal Rathke's pouch development

absent Rathke's pouch

absent adenohypophysis

abnormal pituitary gland development

abnormal thymus morphology

abnormal thymus development

absent thyroid gland

abnormal mammary gland bud morphology

abnormal mammary placode morphology

absent mammary gland

decreased sebaceous gland number

sebaceous gland atrophy

absent exorbital lacrimal gland

abnormal lacrimal gland development

absent lacrimal gland bud

absent lacrimal glands

abnormal prostate gland branching morphogenesis

decreased prostate gland duct number

increased prostate gland weight

abnormal seminal vesicle morphology

abnormal seminal vesicle development

abnormal branching involved in seminal vesicle morphogenesis

abnormal seminal vesicle muscle layer morphology

abnormal pancreas development

small pancreas

Availability

Mouse Genotype

Fgfr2^m1Sgg/Fgfr2^m1Sgg

Fgfr2^svs/Fgfr2^svs

Fgfr2^tm1.1Dsn/Fgfr2^tm1.1Dsn

Fgfr2^tm2.1Lni/Fgfr2^tm2.1Lni

Fgfr2^tm3Dsn/Fgfr2^tm3Dsn

Fgfr2^tm1.1Dor/Fgfr2^svs

Fgfr2^tm1.1Dsn/Fgfr2⁺

Fgfr2^tm1Dor/Fgfr2^svs

Fgfr2^tm2.3Dsn/Fgfr2⁺

Tg(Pbsn-Fgfr2/Fkbp1a)#Dmsp/0

Fgfr2^tm1Dor/Fgfr2^tm1Dor
Tg(Pax6-cre,GFP)1Pgr/0 (conditional)

Fgfr2^tm1Dor/Fgfr2^tm1Dor
Tg(KRT5-cre)5132Jlj/0 (conditional)

Fgfr2^tm1Dsn/Fgfr2^tm1Dsn
Tg(KRT5-cre)5132Jlj/0 (conditional)

Fgfr2^tm1Ewj/Fgfr2⁺
Tg(EIIa-cre)C5379Lmgd/0 (conditional)

Fgfr2^tm2Dsn/Fgfr2⁺
Tg(Pgk1-cre)1Lni/0 (conditional)

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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